ClinX Interview: Dr. Efrem Castillo on Value-Based Care

How does a family physician go from launching five clinics before finishing residency to leading Medicare and Retirement for UnitedHealthcare? In this episode of the ClinX Podcast, Dr. Efrem Castillo, EVP at Render and former CMO at Optum and WellMed, shares how his “don’t say no” philosophy shaped a career defined by entrepreneurial grit, value-based care innovation, and national healthcare leadership. His story is a powerful lesson in resilience, advocacy, and the enduring value of community—essential insights for physicians seeking to grow their careers, embrace healthcare leadership, and make a broader impact in today’s evolving system.